Scientists have discovered a new way to predict which melanomas are hot or cold. Tumors with mutations in genes leading to over-activation of the NF-kB signaling pathway were more than three times as likely to respond to anti-PD1 immunotherapy compared with tumors in which these changes were absent, stated a University of Colorado Cancer Center study presented at the American Association for Cancer Research (AACR) Annual Meeting 2019.
The problem is that it's been impossible to distinguish ...
Scientists have discovered a new way to predict which melanomas are hot or cold. Tumors with mutations in genes leading to over-activation of the NF-kB signaling pathway were more than three times as likely to respond to anti-PD1 immunotherapy compared with tumors in which these changes were absent, stated a University of Colorado Cancer Center study presented at the American Association for Cancer Research (AACR) Annual Meeting 2019.
The problem is that it's been impossible to distinguish ...